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Accueil du site > Actualités > Le trachome est responsable de cicatrice, même en l’absence de (...)

Le trachome est responsable de cicatrice, même en l’absence de manifestation clinique

mercredi 8 avril 2009.

Dans le cadre de cette étude longitudinale menée avec des enfants tanzaniens d’un village en situation d’hyperendémie trachomateuse, l’infection à long terme par Chlamydia trachomatis a été un facteur de risque de cicatrice, même en l’absence de signes cliniques en permanence. Le suivi durant cinq ans des 189 enfants âgés de moins de 10 ans au début de l’étude, et ayant été atteints cliniquement de trachome pendant au moins trois des cinq visites des dix-huit premiers mois, a montré que le risque de complications cicatricielles est identique en cas de trachome clinique grave et pérenne sans infection en permanence (35 % ; 22 enfants [11,6 %]), en cas d’infection permanente attestée sans manifestation clinique permanente (44,4 %, 9 enfants [4,8 %]) ou en cas d’infection permanente associée à un trachome grave et pérenne (31,2 %, 16 enfants [8,5 %]), et il est plus élevé qu’en cas d’atteinte clinique ou d’infection sporadique (15,2 %) ou en l’absence de maladie (6,8 % ; P = 0,0002).

HG

Wolle MA, et al. Constant ocular infection with Chlamydia trachomatis predicts risk of scarring in children in Tanzania. Ophthalmology 2009 ;116:243-7.



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